Taking SILIQ

If your doctor decides that you or a caregiver can give the injections at home, you will need to be trained on the right way to inject SILIQ. Your doctor will take you through the steps to prepare, inject, and dispose of SILIQ. Do not try to inject SILIQ before this training.

When your medicine arrives, please check to be sure that you have 4 syringes. Those will last for the first month of treatment. All of your refills after that will have 2 syringes per month.

 

Start

Week 1

Week 2

Once your SILIQ arrives,
take 1 dose a week
for 3 weeks.

Week 3

Week 4

Week 5

Week 6

Week 7

...

After that, take SILIQ once every 2 weeks. Consistent dosing gives you consistent results — your medicine works best when used on the right schedule. If you ever miss a dose, talk your doctor.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Remember the 4 easy steps

It may take a few times before you’re completely comfortable injecting SILIQ on your own. Refer to these steps and the video below as often as you need. Pretty soon, injecting SILIQ will become just another routine in your life. Want an easy way to help remember how to take SILIQ?

Set Up, Select, Squeeze, and Inject SILIQ.

1

Set up

First, set up all your supplies.

2

Select

Select an injection site, and with clean hands, wipe the site with an alcohol swab. Your doctor will give you instructions on how to best select an injection site.

3

Squeeze

Squeeze the injection site to create a firm surface.

4

Inject SILIQ

Inject the prefilled syringe into the site and press the plunger until all the medicine has been injected.

Once you have completed the injection and removed the
prefilled syringe, place it in a needle disposal container.

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Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
  • who have tried another systemic therapy that didn’t work or stopped working

It is not known if SILIQ is safe and effective in children.

Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

  • new or worsening depression, anxiety, or mood problems
  • thoughts of suicide, dying, or hurting yourself
  • attempt to commit suicide, or acting on dangerous impulses
  • other unusual changes in your behavior or mood

Your doctor will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your doctor.

Serious Infections:

SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with SILIQ and may treat you for TB before starting SILIQ if you have TB or a history of it
  • You and your doctor need to watch closely for signs and symptoms of infection during treatment with SILIQ, including fever, sweats, chills, shortness of breath, stomach issues, muscle aches, cough, sore throat or trouble swallowing, warm/red/painful skin sores, burning while urinating or more frequent urination

Who should not use SILIQ?

Do not use SILIQ if you have Crohn’s disease. Tell your doctor if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.

Before starting SILIQ, tell your doctor if you:

  • have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
  • have an infection that does not go away or keeps coming back
  • have TB or have been in close contact with someone with TB
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ
  • are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use SILIQ?

See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your doctor tells you to use it.

What are possible side effects of SILIQ?

SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”

The most common side effects of SILIQ include:

  • Joint pain
  • Headache
  • Tiredness
  • Diarrhea
  • Mouth or throat pain
  • Nausea
  • Muscle pain
  • Injection site reactions
  • Flu
  • Low white blood cell count (neutropenia)
  • Fungal infections of the skin

Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.


SLQ.0143.USA.20

Indication
Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
  • who have tried another systemic therapy that didn’t work or stopped working

It is not known if SILIQ is safe and effective in children.

Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

  • new or worsening depression, anxiety, or mood problems
  • thoughts of suicide, dying, or hurting yourself
  • attempt to commit suicide, or acting on dangerous impulses
  • other unusual changes in your behavior or mood

Your doctor will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your doctor.

Serious Infections:

SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with SILIQ and may treat you for TB before starting SILIQ if you have TB or a history of it
  • You and your doctor need to watch closely for signs and symptoms of infection during treatment with SILIQ, including fever, sweats, chills, shortness of breath, stomach issues, muscle aches, cough, sore throat or trouble swallowing, warm/red/painful skin sores, burning while urinating or more frequent urination.

Who should not use SILIQ?

Do not use SILIQ if you have Crohn’s disease. Tell your doctor if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.

Before starting SILIQ, tell your doctor if you:

  • have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
  • have an infection that does not go away or keeps coming back
  • have TB or have been in close contact with someone with TB
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ
  • are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use SILIQ?

See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your doctor tells you to use it.

What are possible side effects of SILIQ?

SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”

The most common side effects of SILIQ include:

  • Joint pain
  • Headache
  • Tiredness
  • Diarrhea
  • Mouth or throat pain
  • Nausea
  • Muscle pain
  • Injection site reactions
  • Flu
  • Low white blood cell count (neutropenia)
  • Fungal infections of the skin

Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.