Medical Studies
How SILIQ Works
Taking SILIQ
Everyone is different, but many patients who took part in medical studies became totally clear.
Almost 9 of 10 patients saw half of their psoriasis disappear in the first month of treatment with SILIQ. On average, patients were about 95% clear at 3 months and beyond.*
*Patients were evaluated for nearly 4 years in a medical study and had about 95% average clearance until the study ended.
SILIQ stops the action of a family of 4 proteins involved in psoriasis by blocking the gateway through which these proteins work. Other biologic medicines that work against this family of proteins target one protein from this group and have no effect on the other 3 proteins. So even if you’ve been around the block with other treatments without the results you want, don’t give up Ask your doctor if SILIQ may work for you.
If your healthcare provider decides that you or a caregiver can give the injections at home, you will need to be trained on the right way to inject SILIQ. Your healthcare provider will take you through the steps to prepare, inject, and dispose of SILIQ. Do not try to inject SILIQ before this training.
When your medicine arrives, please check to be sure that you have 4 syringes. Those will last for the first month of treatment. All of your refills after that will have 2 syringes per month.
Once your SILIQ arrives, take one dose a week for 3 weeks.
After that, take SILIQ once every 2 weeks. Consistent dosing gives you consistent results – your medicine works best when used on the right schedule.
It may take a few times before you’re completely comfortable injecting SILIQ on your own. Refer back to these steps and the video below as often as you need. Pretty soon, injecting SILIQ will become just another routine in your life. Want an easy way to help remember how to take SILIQ? Set Up, Select, Squeeze, and Inject SILIQ.
First, set up all your supplies.
Select an injection site, and with clean hands, wipe the site with an alcohol swab.
Squeeze the injection site to create a firm surface.
Inject the prefilled syringe into the site and press the plunger until all the medicine has been injected.
Once you have completed the injection and removed the prefilled syringe, place it in your needle disposal container.
Treatment results with SILIQ can be dramatic. See how SILIQ is helping patients like you get totally clear.
These photos are of actual patients treated with SILIQ in clinical trials. Photos have not been retouched. Individual results may vary.
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What is SILIQ?
SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:
It is not known if SILIQ is safe and effective in children.
Suicidal thoughts or behavior:
Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:
Serious Infections:
SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.
Who should not use SILIQ?
Do not use SILIQ if you have Crohn’s disease. Tell your healthcare provider if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.
Before starting SILIQ, tell your healthcare provider if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
How should I use SILIQ?
See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your healthcare provider tells you to use it.
What are possible side effects of SILIQ?
SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”
The most common side effects of SILIQ include:
Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.
Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.
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SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis: who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and who have tried another systemic therapy that didn’t work or stopped working It is not known if SILIQ is safe and effective in children.
Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms: who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and who have tried another systemic therapy that didn’t work or stopped working
have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
have an infection that does not go away or keeps coming back
have TB or have been in close contact with someone with TB
have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby