Ready to try something different?

Living with moderate to severe plaque psoriasis tests your strength and tries your patience. The typical treatment plan goes something like this — if at first you don’t succeed, try, try again.

Well, if trying again and again is getting you nowhere, you still have a reason to believe. Many others like you who weren't seeing the results they wanted with other psoriasis injections (biologics) were able to reach 100% clear skin with SILIQ.

A medical study with 39 patients

After 4 months taking SILIQ, patients who had previously failed to become 75% clear on Cosentyx or Taltz achieved significant improvement.

Almost 3 out of 10 became 100% clear with SILIQ More than 4 out of 10 became 90% clear with SILIQ
More than 6 out of 10 became 90% clear with SILIQ Almost 4 out of 10 became 100% clear with SILIQ

Data from 124 people

After 1 year taking SILIQ, many patients whose psoriasis remained moderate after taking Stelara saw significant results.

Data from 150 people

After 3 months taking SILIQ, many patients who had previously tried Humira, Remicade, or Enbrel without success were rescued from the loop of treatment failure.

More than 6 out of 10 became 90% clear with SILIQ Almost 4 out of 10 became 100% clear with SILIQ

Go for it all
with SILIQ

Everyone is different, but many people who took part in medical studies became 100% clear.

More than 4 out of every 10 patients were totally clear at 3 months with SILIQ More than 4 out of every 10 patients were totally clear at 3 months with SILIQ

at 3 months with SILIQ

In the same study, only 1 of every 200 people were clear at 3 months when treated with placebo.

Nearly 7 out of every 10 patients were 100% clear at 1 year and 2 years with SILIQ Nearly 7 out of every 10 patients were 100% clear at 1 year and 2 years with SILIQ

at 1 year and 2 years with SILIQ

In the same study, no one was clear at 1 year when treated with placebo.

So, what about patients who weren’t completely clear?

Almost 9 of 10 people saw half of their psoriasis clear in the first month of treatment with SILIQ. On average, people were about 95% clear at 3 months and beyond.*

*Patients were evaluated for nearly 4 years in a medical study and had about 95% average clearance until the study ended.

Psoriasis patient with BSA 0% at 3 months with SILIQ Psoriasis patient with BSA 0% at 3 months with SILIQ

Nothing else works quite like SILIQ

SILIQ fights plaque psoriasis by stopping all 4 cytokines (proteins) in the IL-17 family. Unlike SILIQ, other IL-17 psoriasis injections (biologics) only target 1 protein from this group and have no effect on the other 3.

See how SILIQ works for yourself by watching the video below.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Have questions?

Visit our FAQs for a quick guide to what you need to know about SILIQ.

Psoriasis patient discussing SILIQ treatment with dermatologist Psoriasis patient discussing SILIQ treatment with dermatologist
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Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
  • who have tried another systemic therapy that didn’t work or stopped working

It is not known if SILIQ is safe and effective in children.

Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

  • new or worsening depression, anxiety, or mood problems
  • thoughts of suicide, dying, or hurting yourself
  • attempt to commit suicide, or acting on dangerous impulses
  • other unusual changes in your behavior or mood

Your doctor will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your doctor.

Serious Infections:

SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with SILIQ and may treat you for TB before starting SILIQ if you have TB or a history of it
  • You and your doctor need to watch closely for signs and symptoms of infection during treatment with SILIQ, including fever, sweats, chills, shortness of breath, stomach issues, muscle aches, cough, sore throat or trouble swallowing, warm/red/painful skin sores, burning while urinating or more frequent urination

Who should not use SILIQ?

Do not use SILIQ if you have Crohn’s disease. Tell your doctor if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.

Before starting SILIQ, tell your doctor if you:

  • have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
  • have an infection that does not go away or keeps coming back
  • have TB or have been in close contact with someone with TB
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ
  • are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use SILIQ?

See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your doctor tells you to use it.

What are possible side effects of SILIQ?

SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”

The most common side effects of SILIQ include:

  • Joint pain
  • Headache
  • Tiredness
  • Diarrhea
  • Mouth or throat pain
  • Nausea
  • Muscle pain
  • Injection site reactions
  • Flu
  • Low white blood cell count (neutropenia)
  • Fungal infections of the skin

Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.

Indication
Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

Indication and Important Safety Information

SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment) and
  • who have tried another systemic therapy that didn’t work or stopped working

It is not known if SILIQ is safe and effective in children.

Suicidal thoughts or behavior:

Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:

  • new or worsening depression, anxiety, or mood problems
  • thoughts of suicide, dying, or hurting yourself
  • attempt to commit suicide, or acting on dangerous impulses
  • other unusual changes in your behavior or mood

Your doctor will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your doctor.

Serious Infections:

SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your doctor should check you for tuberculosis (TB) before starting treatment with SILIQ and may treat you for TB before starting SILIQ if you have TB or a history of it
  • You and your doctor need to watch closely for signs and symptoms of infection during treatment with SILIQ, including fever, sweats, chills, shortness of breath, stomach issues, muscle aches, cough, sore throat or trouble swallowing, warm/red/painful skin sores, burning while urinating or more frequent urination.

Who should not use SILIQ?

Do not use SILIQ if you have Crohn’s disease. Tell your doctor if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.

Before starting SILIQ, tell your doctor if you:

  • have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
  • have an infection that does not go away or keeps coming back
  • have TB or have been in close contact with someone with TB
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ
  • are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use SILIQ?

See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your doctor tells you to use it.

What are possible side effects of SILIQ?

SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”

The most common side effects of SILIQ include:

  • Joint pain
  • Headache
  • Tiredness
  • Diarrhea
  • Mouth or throat pain
  • Nausea
  • Muscle pain
  • Injection site reactions
  • Flu
  • Low white blood cell count (neutropenia)
  • Fungal infections of the skin

Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.