Try Something Different
How SILIQ Works
Taking SILIQ
Living with moderate to severe plaque psoriasis tests your strength and tries your patience. The typical treatment plan goes something like this — if at first you don’t succeed, try, try again.
Well, if trying and trying again is getting you nowhere, you still have a reason to believe. Many others who, like you, weren’t seeing the results they wanted with other biologic treatments were able to reach 100% clear skin with SILIQ.
A medical study with 39 patients
After 4 months taking SILIQ, patients who had previously failed to become 75% clear on Cosentyx or Taltz achieved significant improvement.
Data from 124 people
After 1 year taking SILIQ, many patients whose psoriasis remained moderate after taking Stelara saw significant results.
Data from 150 people
After 3 months taking SILIQ, many patients who had previously tried Humira, Remicade, or Enbrel without success were rescued from the loop of treatment failure.
Everyone is different, but many people who took part in medical studies became 100% clear.
at 3 months with SILIQ In the same study, only 1 of every 200 people were clear at 3 months when treated with placebo.
at 1 year and 2 years with SILIQ In the same study, no one was clear at 1 year when treated with placebo.
Almost 9 of 10 people saw half of their psoriasis clear in the first month of treatment with SILIQ. On average, people were about 95% clear at 3 months and beyond.*
*Patients were evaluated for nearly 4 years in a medical study and had about 95% average clearance until the study ended.
SILIQ stops the action of a family of 4 proteins involved in psoriasis by blocking the gateway through which these proteins work. Other biologics that work against this family of proteins target 1 protein from this group and have no effect on the other 3 proteins. So even if you’ve gone around and around with other treatments without the results you want, don’t lose hope. Ask your doctor if SILIQ is the bio-logical next step to treatment success.
If your doctor decides that you or a caregiver can give the injections at home, you will need to be trained on the right way to inject SILIQ. Your doctor will take you through the steps to prepare, inject, and dispose of SILIQ. Do not try to inject SILIQ before this training.
When your medicine arrives, please check to be sure that you have 4 syringes. Those will last for the first month of treatment. All of your refills after that will have 2 syringes per month.
Once your SILIQ arrives, take 1 dose a week for 3 weeks.
After that, take SILIQ once every 2 weeks. Consistent dosing gives you consistent results – your medicine works best when used on the right schedule.
It may take a few times before you’re completely comfortable injecting SILIQ on your own. Refer to these steps and the video below as often as you need. Pretty soon, injecting SILIQ will become just another routine in your life. Want an easy way to help remember how to take SILIQ?
Set Up, Select, Squeeze, and Inject SILIQ.
First, set up all your supplies.
Select an injection site, and with clean hands, wipe the site with an alcohol swab.
Squeeze the injection site to create a firm surface.
Inject the prefilled syringe into the site and press the plunger until all the medicine has been injected.
Once you have completed the injection and removed the prefilled syringe, place it in a needle disposal container.
SILIQ is helping people like you achieve 100% clear skin.
These photos are of actual patients treated with SILIQ in clinical trials. Photos have not been retouched. Individual results may vary.
Ready to make an appointment, but don’t have a dermatologist? We can help.
SILIQ® injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:
It is not known if SILIQ is safe and effective in children.
Suicidal thoughts or behavior:
Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions. Get medical help right away if you or a family member notices that you have any of the following symptoms:
Your doctor will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your doctor.
Serious Infections:
SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.
Who should not use SILIQ?
Do not use SILIQ if you have Crohn’s disease. Tell your doctor if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.
Before starting SILIQ, tell your doctor if you:
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
How should I use SILIQ?
See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your doctor tells you to use it.
What are possible side effects of SILIQ?
SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”
The most common side effects of SILIQ include:
Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.
Click here for full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.
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SILIQ® injection is indicated for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy and have failed to respond or have lost response to other systemic therapies.
WARNING: SUICIDAL IDEATION AND BEHAVIOR
Suicidal ideation and behavior, including completed suicides, have occurred in patients treated with SILIQ. Prior to prescribing SILIQ, weigh the potential risks and benefits in patients with a history of depression and/or suicidal ideation or behavior. Patients with new or worsening suicidal ideation and behavior should be referred to a mental health